Diclofenac Sodium - An Overview
Gastrointestinal (GI): NSAIDs that block COX-one action have correlations with GI troubles a result of the inhibition with the synthesis of gastroprotective agents which include PGE2 and other prostaglandins. This inhibition results in lowered mucin output by gastric epithelial cells, less bicarbonate secretion, and fewer epithelial mobile turnover